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CHL 5225 H -- ADVANCED STATISTICAL METHODS FOR CLINICAL TRIALS



 

Bayesian Approaches in Clinical Trials



Required Reading:

  1. Willan AR. Bayesian methods provide important advantages for the design, analysis and interpretation of clinical studies.
    In: Berger VW, Zhang X. (Eds.) Important Considerations for Clinical Trial Methodologies 2013; Future Medicine, pages 116-128. (eISBN 978-1-909453-31-9) Download



References:

  1. Spiegelhalter DJ, Abrams KR, Myles JP. Bayesian Approaches to Clinical Trials and Health-Care Evaluation 2004; Wiley, Chichester.

  2. Goodman SN. Toward evidence-based medical statistics. 1: The P value fallacy. Ann. Intern. Med. 1999; 130(12): 995-1004.

  3. Goodman SN. Toward evidence-based medical statistics. 2: The Bayes factor. Ann. Intern. Med. 1999 130(12): 1005-1013.

  4. Kadane JB. Prime time for Bayes. Contr. Clin. Trials 1995; 16(5): 313-318.

  5. Spiegelhalter DJ, Myles JP, Jones DR Abrams KR. An Introduction to Bayesian Methods in Health Technology Assessment. BMJ 1999 319(7208): 508-512.


Class Notes